Spike & Dru is a trade paperback collecting comic stories based on the Buffy television series. The book contains four stories, all starring the characters Spike and Drusilla.
All's Fair[]
- Story description: In 1933, Spike and Dru are at the World's Fair. However, some very vengeful and deadly vampire hunters want vengeance against Spike for killing their relative Xin Rong.
- Continuity: Set in 1933, with flashbacks to 1900.
The Queen of Hearts[]
- Story description: Spike and Dru are travelling to Sunnydale, but first stop off at St. Louis to try some riverboat gambling. The detour ends up less relaxing than they might have hoped.
- Continuity: Set before Buffy Season 2 episode School Hard.
Paint the Town Red[]
- Story description: Spike is irritated by Drusilla's passion for Angelus. Their relationship comes to a heated end and Spike goes to Turkey for a break. Dru hunts him down with someone new, a necromancer. She wants to even the scores but soon makes trouble for everyone.
- Continuity: Set after Buffy Season 2 episode Becoming II.
- Trivia: This is the story co-authored by James Marsters, the actor who played Spike on the Buffy the Vampire Slayer television show.
Who Made Who[]
- Story description: Spike and Dru are a newly made up couple in Brazil. Yet Dru's attention once again drifts away and Spike spoils some partying.
- Continuity: Set in Buffy Season 3, after the episode "Lovers Walk".
- Trivia: This is a ten page short story. It originally appeared in the comic one shot "Lovers Walk".